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The word internal in IQC implicates that repeatability conditions are achieved Thus monitoring the precision as the objective of IQC concerns not reproducibility or interlaboratory precision but only repeatability or intralaboratory precision In fact, the monitoring of accuracy of an analytical method in IQC can be translated into the monitoring of the analytical system [8] Two aspects are important for IQC: (1) the analysis of control materials such as reference materials or spiked samples to monitor trueness and (2) replication of analysis to monitor precision Of high value in IQC are also blank samples and blind samples Both IQC aspects form a part of statistical control, a tool for monitoring the accuracy of an analytical system In a control chart, such as a Shewhart control chart, measured values of repeated analyses of a reference material are plotted against the run number.

From the Dock, click the System Preferences icon (the light switch with the Apple symbol). The System Preferences window opens. Under Internet and Network, click the Network icon. Just above the lower pane, click the Proxies button. This shows the proxy selection options. In the left-hand pane, highlight the service for which you want to configure a proxy. Then, to the left, enter the IP number and port number of the proxy server. Back in the left-hand pane, click the checkbox next to the service to indicate that the proxy server should be used. When you have finished click Apply Now.

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In contrast to quality management systems, which have clear parallels with PAT (ie, reduction of quality variation), the links between PAT and lean manufacturing are less direct In fact, while quality management systems are concerned with process analysis of quality variation, lean ow path management is concerned with process analysis of production time variation Furthermore, the core concepts of lean manufacturing, however, provide the technology platform which the pharmaceutical industry will use to derive gains in production ef ciency from the adoption of PAT Without considering the impact of PAT on production ef ciency [ie, the return on investment (ROI) from implementing PAT], industry would have very little impetus to voluntarily embrace PAT The following paragraphs are intended to provide a brief introduction to lean manufacturing; later portions of this chapter will discuss the business drivers for implementation of PAT.

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Create dynamic Code 39 barcodes with the help of included formulas. BCW_Code39(): Encodes the barcode as Code 39 . This formula adds asterisks and ...

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